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The white spots is pus. My first guess is Streptococcus: Ibuprofen will work if it is strep, but be sure you are not allergic to that, because many people are, including me. It wasn't fun to find out. OR, You probably have infectious Mononucleosis is you have had a fever, red spots on the top of your mouth, or any little rash-like dots on any other part of your body, and fatigue prolonged for more than one week. OR, you could have Herpangina (I doubt it, though): -sores in your throat -headache -loss of appetite -sore arms, stomach, legs, or back If you just have a cold virus (Is there mild soreness and swelling of the lymph nodes in your neck?). To take care of that, gargle with warm water. Some people prefer warm, salty water. This works great! Try to limit activity, if you can, get plenty of bed rest. If this does persist for up to two weeks, don't be surprised. Sore throats take FOREVER to get away (at least for me, anyway). If it last longer, you probably do have Mononucleosis, and you really will need to see a doctor for a blood test. Go to your local drug store and pick up some Chloraseptic anaesthetic throat spray. You spray it directly on your throat five times, don't swallow, wait 15 seconds, and then spit it out. It's not the best tasting stuff, but it sure does make your throat feel better. Its about seven dollars. I hope you get better before your vacation!